When there is an Active Shooter Alert, which of the following is advised?

In the event of an active shooter alert, seeking shelter in a locked office is a recommended response. This action prioritizes personal safety and minimizes exposure to danger. Securing yourself in a locked room creates a barrier between you and the potential threat, while also allowing for better assessment of the situation. Staying quiet and out of sight can further prevent engagement with the assailant, increasing the chances of survival.

The other options, while they may seem viable, can present significant risks. Engaging the shooter can escalate the situation and endanger your life and the lives of others. Immediately evacuating all patients may not be feasible or safe, depending on the situation, as it could expose individuals to the shooter while attempting to leave. Although looking for the nearest exits is important in an emergency, without knowing the shooter's location, it can be more dangerous than seeking a secure shelter. Therefore, the focused recommendation to hole up in a locked office stands out as the safest initial course of action in an active shooter scenario.